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Simone Carradori Selected Research

Kinesins

1/2022Negative Modulation of the Angiogenic Cascade Induced by Allosteric Kinesin Eg5 Inhibitors in a Gastric Adenocarcinoma In Vitro Model.
1/2022The kinesin Eg5 inhibitor K858 exerts antiproliferative and proapoptotic effects and attenuates the invasive potential of head and neck squamous carcinoma cells.
10/2019Kinesin Eg5 Targeting Inhibitors as a New Strategy for Gastric Adenocarcinoma Treatment.
1/2018The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells.
1/2018Growth arrest and apoptosis induced by kinesin Eg5 inhibitor K858 and by its 1,3,4-thiadiazoline analogue in tumor cells.
1/2016The kinesin Eg5 inhibitor K858 induces apoptosis but also survivin-related chemoresistance in breast cancer cells.
11/2015Synthesis and pharmacological screening of a large library of 1,3,4-thiadiazolines as innovative therapeutic tools for the treatment of prostate cancer and melanoma.

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Simone Carradori Research Topics

Disease

32Neoplasms (Cancer)
12/2022 - 01/2013
14Neurodegenerative Diseases (Neurodegenerative Disease)
08/2022 - 07/2012
12Inflammation (Inflammations)
08/2022 - 01/2015
7Breast Neoplasms (Breast Cancer)
12/2022 - 01/2016
7Alzheimer Disease (Alzheimer's Disease)
01/2022 - 01/2016
6Adenocarcinoma
01/2022 - 06/2017
5Infections
05/2021 - 01/2020
4Glioblastoma (Glioblastoma Multiforme)
12/2022 - 01/2018
4Prostatic Neoplasms (Prostate Cancer)
08/2022 - 07/2012
4Cognitive Dysfunction
06/2021 - 01/2016
3Carcinoma (Carcinomatosis)
01/2022 - 07/2012
3Pancreatic Neoplasms (Pancreatic Cancer)
08/2021 - 12/2019
3Parkinson Disease (Parkinson's Disease)
11/2019 - 01/2018
2COVID-19
12/2022 - 01/2021
2Communicable Diseases (Infectious Diseases)
12/2022 - 05/2020
2Nervous System Diseases (Neurological Disorders)
01/2022 - 01/2015
2Melanoma (Melanoma, Malignant)
01/2022 - 01/2018
2Neuralgia (Stump Neuralgia)
12/2021 - 01/2021
2Mycoses (Diseases, Fungus)
12/2021 - 12/2017
2Memory Disorders (Memory Loss)
06/2021 - 06/2021
2Colorectal Neoplasms (Colorectal Cancer)
04/2021 - 11/2015
2Lung Neoplasms (Lung Cancer)
06/2020 - 03/2016
2Glaucoma
10/2019 - 03/2015
2Glioma (Gliomas)
05/2019 - 01/2018
2Carcinogenesis
05/2019 - 01/2013
2Ulcerative Colitis
03/2019 - 06/2017
2Chronic Pain
01/2018 - 12/2016
2Migraine Disorders (Migraine)
01/2018 - 09/2015
2Intellectual Disability (Idiocy)
12/2017 - 01/2016
2Type 2 Diabetes Mellitus (MODY)
01/2017 - 02/2015
2Alcoholism (Alcohol Abuse)
09/2015 - 07/2012
2Leukemia
03/2014 - 01/2012
1Vertigo (Positional Vertigo)
08/2022
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
08/2022
1Gouty Arthritis
01/2022
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2022
1Atherosclerosis
01/2022
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2022
1Squamous Cell Carcinoma of Head and Neck
01/2022
1Bacterial Infections (Bacterial Infection)
12/2021
1Musculoskeletal Diseases (Musculoskeletal Disease)
11/2021
1Paraganglioma (Paragangliomas)
04/2021

Drug/Important Bio-Agent (IBA)

15Protein Isoforms (Isoforms)IBA
12/2021 - 12/2013
12Carbonic Anhydrases (Carbonic Anhydrase)IBA
12/2022 - 01/2013
12Pharmaceutical PreparationsIBA
12/2022 - 01/2016
11Monoamine Oxidase (MAO)IBA
08/2022 - 07/2012
9EnzymesIBA
06/2020 - 07/2012
8Biological ProductsIBA
12/2021 - 07/2015
8AntioxidantsIBA
06/2021 - 01/2018
7KinesinsIBA
01/2022 - 11/2015
5Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2012
4Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
08/2022 - 07/2012
4TubulinIBA
01/2022 - 01/2012
4SulfonamidesIBA
10/2020 - 09/2014
3Carbonic Anhydrase InhibitorsIBA
12/2022 - 03/2015
3Antidepressive Agents (Antidepressants)IBA
08/2022 - 07/2014
3Carbon MonoxideIBA
11/2021 - 01/2021
3AnthelminticsIBA
04/2021 - 05/2017
3benzimidazoleIBA
04/2021 - 05/2017
3Histone Acetyltransferases (Histone Acetyltransferase)IBA
06/2020 - 03/2014
2Anti-Bacterial Agents (Antibiotics)IBA
12/2022 - 01/2021
2SLC-0111IBA
12/2022 - 10/2020
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2021 - 01/2018
2Doxorubicin (Adriamycin)FDA LinkGeneric
12/2021 - 02/2021
2Antineoplastic Agents (Antineoplastics)IBA
12/2021 - 11/2015
2Aromatase InhibitorsIBA
12/2021 - 09/2018
2Scopolamine (Hyoscine)FDA Link
06/2021 - 06/2021
2BenzimidazolesIBA
04/2021 - 12/2019
2Carbonic Anhydrase IXIBA
01/2021 - 12/2017
2Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2015
2AcidsIBA
12/2020 - 01/2018
2Angiogenesis InhibitorsIBA
06/2020 - 07/2012
2SurvivinIBA
01/2018 - 01/2016
2Antimitotic AgentsIBA
01/2018 - 11/2015
2SaccharinIBA
12/2017 - 03/2014
2ThiazolesIBA
03/2016 - 01/2012
2disalicylaldehyde ethylenediamine (salen)IBA
02/2015 - 12/2013
2ZincIBA
01/2015 - 03/2014
2carbonic anhydrase XIIIBA
03/2014 - 12/2013
1BenzenesulfonamidesIBA
12/2022
1ThiosemicarbazonesIBA
12/2022
1Cholinesterases (Cholinesterase)IBA
08/2022
1diazonaphthalenedisulfonic acid (NDS)IBA
04/2022
1InflammasomesIBA
01/2022
1fisetinIBA
01/2022
1Neuroprotective AgentsIBA
01/2022
1Interleukin-6 (Interleukin 6)IBA
12/2021
1PlatinumIBA
12/2021
1Cisplatin (Platino)FDA LinkGeneric
12/2021
1Aromatase (CYP19)IBA
12/2021
1TriazolesIBA
12/2021
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
12/2021
1IndazolesIBA
12/2021
1pyrazoleIBA
11/2021
1Dinoprostone (PGE2)FDA Link
11/2021
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
11/2021
1Peptides (Polypeptides)IBA
05/2021
1Ether (Diethyl Ether)IBA
03/2021

Therapy/Procedure

14Therapeutics
01/2022 - 07/2012
2Drug Therapy (Chemotherapy)
12/2021 - 11/2015